99% USP Azelastine Hydrochloride Powder Antiallergic Medication Active Pharmaceutical Ingredients
a5610;azeptin;e-0659;w-2979m;AZELASTINE HCL;AZELASTINE HYDROCHLORIDE;4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)-phthalazin-1-one hydrochloride;4-[(4-Chlorophenyl)methyl]-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1(2H)-phthalazinone Hydrochloride
CAS No.: 79307-93-0
Appearance: White Crystalline Powder
Place of Origin: China
Method of Analysis: HPLC
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Packaging Details: Very discreet. As required.
Delivery Time: Within 24 hours after payment
Payment Terms: T/T, Western Union, MoneyGram, Bitcoin
Supply Ability: 1000 ton/month
Minimum Order Quantity: 10g
Azelastine is a potent, second-generation, selective, histamine antagonist (histamine-H1-receptor antagonist) used as a first line therapy of mild intermittent, moderate/severe intermittent and mild persistent rhinitis (new classification system for rhinitis).
Azelastine has been formulated both as a nasal spray and as eye drops and are available worldwide under many brand names.
Azelastine nasal spray is indicated for the local treatment of the symptoms of seasonal allergic rhinitis and perennial allergic rhinitis, such as rhinorrhea, sneezing and nasal pruritus in adults and children 5 years of age and older. In some countries, it is also indicated for the treatment of vasomotor rhinitis in adults and children ≥ 12 years old.Azelastine eyes drops are indicated for the local treatment of seasonal and perennial allergic conjunctivitis.
Azelastine is safe and well tolerated in both adults and children with allergic rhinitis.Bitter taste, headache, nasal burning and somnolence are the most frequently reported adverse events. US prescribing recommendations warn against the concurrent use of alcohol and/or other central nervous system depressants, but to date there have been no studies to assess the effects of azelastine nasal spray on the CNS in humans. More recent studies have shown similar degrees of somnolence (approx. 2%) compared with placebo treatment. The problem of bitter taste may be reduced by correct application of the nasal spray (i.e. slightly tipping the head forward and not inhaling the medication too deeply), or alternatively using the azelastine/sucralose formulation.
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Tag: Active Pharmaceutical Ingredients, Pharmaceutical Intermediates, Pharmaceuticals, Pharmaceutical Chemicals, Raw Powder, Antiallergic Medication, Antihistamines