Wuhan Hezhong Bio-Chemical Manufacture Co., Ltd.

Levodopa, Parkinson Treatment, Active Pharmaceutical Ingredients manufacturer / supplier in China, offering 99% USP Levodopa Powder Parkinson Treatment Active Pharmaceutical Ingredients, Pramlintide Acetate Steroid Powders, Raw Superdrol Steroid Powder and so on.

Supplier Homepage Product List muscle fitness series 99% USP Levodopa Powder Parkinson Treatment Active Pharmaceutical Ingredients

99% USP Levodopa Powder Parkinson Treatment Active Pharmaceutical Ingredients

FOB Price: Get Latest Price
Min. Order: 10 g
Port: Hong Kong, Hong Kong
Production Capacity: 1000 Ton/Month
Payment Terms: T/T, Western Union, Money Gram, Bitcoin

Basic Info.

Model NO.:59-92-7
Powder:Yes
Customized:Non-Customized
Certification:USP, BP
Suitable for:Adult
State:Solid
Purity:>99%
Grade:Medicine Grade
Trademark:SGS
Transport Package:Very Discreet. as Required.
Specification:USP
Origin:China

Product Description

USP Levodopa Powder Genuine Levodopa Powder Legit Levodopa Powder Order Levodopa Powder Buy Levodopa Powder Get Levodopa Powder Online Levodopa Powder Source Levodopa Powder 
 
Product Details:
Alias: L-DOPA, L-3,4-dihydroxyphenylalanine, 3-(3,4-Dihydroxyphenyl)-L-alanine, L-3-(3,4-Dihydroxyphenyl)alanine
CAS No.: 59-92-7 
MF: C9H11NO4
MW: 197.19
Purity: 99%
Appearance: White or Off-White Crystalline Powder
Place of Origin: China
Standard: USP
Certification: SGS
Method of Analysis: HPLC
 
Payment & Shipping Terms:
Price: Negotiable
Packaging Details: Very discreet. As required.
Delivery Time: Within 24 hours after payment
Payment Terms: T/T, Western Union, MoneyGram, Bitcoin 
Supply Ability: 1000 ton/month
Minimum Order Quantity: 10g
 
Usage:
L-DOPA crosses the protective blood-brain barrier, whereas dopamine itself cannot. Thus, L-DOPA is used to increase dopamine concentrations in the treatment of Parkinson's disease and dopamine-responsive dystonia. This treatment was made practical and proven clinically by George Cotzias and his coworkers, for which they won the 1969 Lasker Prize. Once L-DOPA has entered the central nervous system, it is converted into dopamine by the enzyme aromatic L-amino acid decarboxylase, also known as DOPA decarboxylase. Pyridoxal phosphate (vitamin B6) is a required cofactor in this reaction, and may occasionally be administered along with L-DOPA, usually in the form of pyridoxine.
Besides the central nervous system, L-DOPA is also converted into dopamine from within the peripheral nervous system. Excessive peripheral dopamine signaling causes many of the adverse side effects seen with sole L-DOPA administration. To bypass these effects, it is standard clinical practice to coadminister (with L-DOPA) a peripheral DOPA decarboxylase inhibitor (DDCI) such as carbidopa (medicines containing carbidopa, either alone or in combination with L-DOPA, are branded as Lodosyn (Aton Pharma) Sinemet (Merck Sharp & Dohme Limited), Pharmacopa (Jazz Pharmaceuticals), Atamet (UCB), and Stalevo (Orion Corporation) or with a benserazide (combination medicines are branded Madopar or Prolopa), to prevent the peripheral synthesis of dopamine from L-DOPA. Coadministration of pyridoxine without a DDCI accelerates the peripheral decarboxylation of L-DOPA to such an extent that it negates the effects of L-DOPA administration, a phenomenon that historically caused great confusion.
In addition, L-DOPA, co-administered with a peripheral DDCI, has been investigated as a potential treatment for restless leg syndrome. However, studies have demonstrated "no clear picture of reduced symptoms".
The two types of response seen with administration of L-DOPA are:
The short-duration response is related to the half-life of the drug.
The longer-duration response depends on the accumulation of effects over at least two weeks, during which ΔFosB accumulates in nigrostriatal neurons. In the treatment of Parkinson's disease, this response is evident only in early therapy, as the inability of the brain to store dopamine is not yet a concern.
 
Competitive Advantage:
1. Rich experience.
We specialize in this field for many years. Our active pharmaceutical ingredients have been exported to overseas, like Europe, Africa, Asia, America and other countries. And we have got very good feedback from our customers, and established long friendly relations of cooperation.
2. Great quality, purity and favorable.
 Good quality is one secret for our success. Welcome order the samples, MOQ just 10 grams.
3. Safest and fastest delivery.
 We have adequate stock, and can arrange the delivery within 24hours when receiving the payment. Tracking number would be informed quickly after shipment. We can ship as much as you order. Shipping methods of different order amount vary.
4. Good after-sales service.
24/7 is available. Tell the package update info ASAP. And try our best to solve various problems customers encounter!
5. Experiential shopping
 
Tag: Active Pharmaceutical Ingredients, Pharmaceutical Intermediates, Pharmaceuticals, Pharmaceutical Chemicals, Raw Powder, Parkinson Treatment
 
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Wuhan Hezhong Bio-Chemical Manufacture Co., Ltd.

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