99% USP Melatonin Powder Steroids Sleep Disorder Treatment Bodybuilding
Alias: N-acetyl-5-methoxy tryptamine, Acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-, Acetamide, N-[2-(5-methoxyindol-3-yl)ethyl]-, Acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl], Melatonin(N-Acetyl-5-methoxytryptamine), n-(2-(5-methoxy-1h-indol-3-yl)ethyl)-acetamid, n-(2-(5-methoxyindol-3-yl)ethyl)-acetamid, N-ACETYL-5-METHOXYTRYPTAMINE, N-[2-(5-METHOXY-1H-INDOL-3-YL)ETHYL]ACETAMIDE
CAS No.: 73-31-4
Appearance: White or Off-White Crystalline Powder
Place of Origin: China
Method of Analysis: HPLC
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Packaging Details: Very discreet. As required.
Delivery Time: Within 24 hours after payment
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Supply Ability: 1000 ton/month
Minimum Order Quantity: 10g
Melatonin has shown promise in treating sleep-wake cycle disorders in children with underlying neurodevelopment difficulties. As add-on to antihypertensive therapy, prolonged-release melatonin has improved blood pressure control in people with nocturnal hypertension.
People with circadian rhythm sleep disorders may use oral melatonin to help entrain (biologically synchronize in the correct phase) to the environmental light-dark cycle. Melatonin reduces sleep onset latency to a greater extent in people with delayed sleep phase disorder than in people with insomnia.
Melatonin has been studied for insomnia in the elderly. Prolonged-release melatonin has shown good results in treating insomnia in older adults. Short-term treatment (up to three months) of prolonged-release melatonin was found to be effective and safe in improving sleep latency, sleep quality, and daytime alertness.
Evidence for use of melatonin as a treatment for insomnia is, as of 2015, insufficient; low-quality evidence indicates it may speed the onset of sleep by 6 minutes. A 2004 review found "no evidence that melatonin had an effect on sleep onset latency or sleep efficiency" in shift work or jet lag, while it did decrease sleep onset latency in people with a primary sleep disorder and it increased sleep efficiency in people with a secondary sleep disorder. A later review found minimal evidence for efficacy in shift work.
Jet lag and shift work:
Melatonin is known to aid in reducing the effects of jet lag, especially in eastward travel, by promoting the necessary reset of the body's sleep-wake phase. If the timing is not correct, however, it can instead delay adaption.
Melatonin appears also to have limited use against the sleep problems of people who work rotating or night shifts.
Tentative evidence shows melatonin may help reduce some types of headaches including cluster headaches.
A 2013 review by the National Cancer Institutes found evidence for use to be inconclusive. A 2005 review of unblinded clinical trials found a reduced rate of death, but that blinded and independently conducted randomized controlled trials are needed.
Melatonin presence in the gallbladder has many protective properties, such as converting cholesterol to bile, preventing oxidative stress, and increasing the mobility of gallstones from the gallbladder.
Protection from radiation:
Both animal and human studies have shown melatonin to protect against radiation-induced cellular damage. Melatonin and its metabolites protect organisms from oxidative stress by scavenging reactive oxygen species which are generated during exposure. Nearly 70% of biological damage caused by ionizing radiation is estimated to be attributable to the creation of free radicals, especially the hydroxyl radical that attacks DNA, proteins, and cellular membranes. Melatonin has been described as a broadly protective, readily available, and orally self-administered antioxidant that is without major known side effects.
Tentative evidence of benefit exists for treating tinnitus.
Melatonin might improve sleep in autistic people. Children with autism have abnormal melatonin pathways and below-average physiological levels of melatonin. Melatonin supplementation has been shown to improve sleep duration, sleep onset latency, and night-time awakenings. However, many studies on melatonin and autism rely on self-reported levels of improvement and more rigorous research is needed.
While the packaging of melatonin often warns against use in people under 18 years of age, available studies suggest that melatonin is an efficacious and safe treatment for insomnia in people with ADHD. However, larger and longer studies are needed to establish long-term safety and optimal dosing.
Melatonin in comparison to placebo is effective for reducing preoperative anxiety in adults when given as premedication. Melatonin may also reduce postoperative anxiety (measured 6 hours after surgery) when compared to placebo.
Some supplemental melatonin users report an increase in vivid dreaming. Extremely high doses of melatonin increased REM sleep time and dream activity in people both with and without narcolepsy.
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